Charline Giroud

Charline Giroud graduated with a PhD degree in Biochemistry, Cellular and Molecular Biology, specialized in Virology, from the School of Medicine of Montpelier, France (2012). She studied the role of cAMP-dependent protein kinase (PKA) incorporated in HIV-1 particle, in early steps of the virus life cycle and showed that PKA acts as a cofactor of reverse transcription initiation.

She worked at the Department of Paediatric Infectious Diseases at the School of Medicine of Emory University of Atlanta, USA (2013) as a postdoctoral fellow. Using high throughput screening strategy combined to cell-based assay development, she discovered and characterized new HIV-1 and Ebola virus entry inhibitors for HIV-1 and Ebola virus entry. She started in the assay development and screening team in May 2017.

Recent publications

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function
Journal article

Fagan V. et al, (2019), Journal of Medicinal Chemistry, 62, 9008 - 9025
Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9
Journal article

Christott T. et al, (2019), SLAS DISCOVERY: Advancing the Science of Drug Discovery, 24, 133 - 141
Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9.
Journal article

Christott T. et al, (2018), SLAS Discov
Development of a YEATS-domain chemical probe
Conference paper

Moustakim M. et al, (2018), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256
Development of a YEATS-domain chemical probe
Conference paper

Moustakim M. et al, (2018), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256

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