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Publications

Microglial inflammation and phagocytosis in Alzheimer's disease: potential therapeutic targets.

Nizami S. et al, (2019), Br J Pharmacol

Alterations on growth and cell organization of Giardia intestinalis trophozoites after treatment with KH-TFMDI, a novel class III histone deacetylase inhibitor.

Gadelha APR. et al, (2019), Int J Med Microbiol

A chemical biology toolbox to study protein methyltransferases and epigenetic signaling.

Scheer S. et al, (2019), Nat Commun, 10

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop.

Agajanian MJ. et al, (2019), Cell Rep, 26, 79 - 93.e8

Deacetylation inhibition reverses PABPN1-dependent muscle wasting

Olie CS. et al, (2019), iScience

An Activity-Based Probe Targeting Non-Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.

D'Ascenzio M. et al, (2018), Angew Chem Int Ed Engl

HCV infection is associated with hepatic and adipose tissue insulin resistance that improves after viral cure.

Lim TR. et al, (2018), Clin Endocrinol (Oxf)

The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.

Nishi R. et al, (2018), Sci Rep, 8

Discovery of an MLLT1/3 YEATS Domain Chemical Probe.

Moustakim M. et al, (2018), Angew Chem Int Ed Engl, 57, 16302 - 16307

Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL).

Heidenreich D. et al, (2018), J Med Chem

A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6.

Priestley RS. et al, (2018), J Pharmacol Toxicol Methods

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Vazquez-Rodriguez S. et al, (2018), Angew Chem Int Ed Engl

Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion.

Buono M. et al, (2018), Nat Commun, 9

Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9.

Christott T. et al, (2018), SLAS Discov

An Activity-based Probe Targeting Non-catalytic, Highly Conserved Amino Acid Residues Within Bromodomains

D’Ascenzio M. et al, (2018)

Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads

Mueller C. et al, (2018)

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression.

Mavrommati I. et al, (2018), Cell Rep, 24, 3404 - 3412

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors

Vazquez-Rodriguez S. et al, (2018)

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.

Wang J. et al, (2018), ACS Chem Biol

Clusterin Is Required for beta-Amyloid Toxicity in Human iPSC-Derived Neurons

Robbins JP. et al, (2018), FRONTIERS IN NEUROSCIENCE, 12

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