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Publications

Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models

Rodriguez-Berriguete G. et al, (2023), Clinical Cancer Research

Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia

Johanssen T. et al, (2023), Frontiers in Oncology, 12

Activity-Based Protein Profiling (ABPP) for Cellular Deubiquitinase (DUB) and Inhibitor Profiling at Deep and High-Throughput Levels.

Jones HBL. et al, (2023), Methods in molecular biology (Clifton, N.J.), 2591, 101 - 122

Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.

Londregan AT. et al, (2022), J Med Chem

A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk.

Rottner AK. et al, (2022), Nature genetics

Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model

O’Brien DP. et al, (2022), Clinical Proteomics, 19

Nilabh Shastri – Towards understanding classical and non-classical MHC-I antigen processing and presentation

Kessler BM., (2022), Cellular Immunology, 382, 104638 - 104638

T cells are ready for the fight against monkeypox.

Wellington D. and Dong T., (2022), Cell host & microbe, 30, 1653 - 1654

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

Céspedes PF. et al, (2022), Nature Communications, 13

Circadian regulation of human immunodeficiency virus type 1 replication

Borrmann H. et al, (2022)

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature.

Lombardi O. et al, (2022), Cell reports, 41

Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism.

Cavounidis A. et al, (2022), Mucosal immunology

Minimalised Three-Dimensional Human Midbrain In Vitro Model for Neurotoxicity Evaluation of DYRK1 Inhibitors

Wan X. et al, (2022)

TAPS: The Development of a Direct and Base-Resolution Sequencing Method for DNA Methylation

Liu Y. and Song C-X., (2022), ACS Chemical Biology

KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity.

Fournier M. et al, (2022), eLife, 11

Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models

Rodriguez-Berriguete G. et al, (2022)

Biochemical and metabolic maladaption defines pathological niches in progressive multiple sclerosis

Grant-Peters M. et al, (2022)

Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant.

Lou H. et al, (2022), Cell research

Performance of Contactless Respiratory Rate Monitoring by Albus HomeTM, an Automated System for Nocturnal Monitoring at Home: A Validation Study

Do W. et al, (2022), Sensors, 22, 7142 - 7142

Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane.

Frank N. et al, (2022), Nature

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