Tika R. Malla
Contact information
Research groups
Tika R. Malla
DPhil
Postdoctoral Scientist - Enzymology and Assay Development
Recent publications
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In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease
Journal article
Miura T. et al, (2023), Nature Chemistry, 15, 998 - 1005
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Accelerating drug target inhibitor discovery with a deep generative foundation model
Journal article
Chenthamarakshan V. et al, (2023), Science Advances, 9
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Turning high-throughput structural biology into predictive inhibitor design.
Journal article
Saar KL. et al, (2023), Proceedings of the National Academy of Sciences of the United States of America, 120
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Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine
Journal article
Brewitz L. et al, (2023), Journal of Medicinal Chemistry, 66, 2663 - 2680
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Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine.
Journal article
Malla TR. et al, (2022), Journal of medicinal chemistry, 65, 7682 - 7696