Postdoctoral Research Assistant
Tamas Szommer earned his MSc in Medicinal Chemistry at the Budapest University of Technology and Economics (under the supervision of Prof. Gyorgy Kalaus) in 2003. He started his industrial career at ComGenex Inc. in Hungary as medicinal chemist and he led numerous custom library and combinatorial library synthesis projects. He also actively participated in the development and introduction of ComGenex’s proprietary central ELN database system. In the meantime he was actively involved into the development of a database for structural evolution (EMIL - `Example-Mediated Innovation for Lead-Evolution` leading by Prof. Toshio Fujita, CompuDrug Inc.). In 2006 ComGenex was acquired by Albany Molecular Research Inc. and Tamas was promoted to Head of Microwave and Parallel Chemistry and he was responsible for the operation and continuous development of the Parallel Chemistry Group in Hungary. He participated in the design and synthesis of small molecular libraries, custom library projects, fragment-based drug discovery projects and numerous natural product-like libraries. In 2012 Tamas successfully managed a technology transfer project at AMRI Hyderabad in India then he joined to ComInnex Inc. (Hungary) for a couple of months to `set up` a medicinal chemistry laboratory.
Tamas joined Prof. Paul Brennan’s Group at the Target Discovery Institute in 2013 to participate in the development of histone lysine demethylases chemical probes.
Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7
Gerken PA. et al, (2017), Angewandte Chemie International Edition, 56, 15555 - 15559
Parallel synthesis of 1,2,4-triazole derivatives using microwave and continuous-flow techniques
Szommer T. et al, (2012), Molecular Diversity, 16, 81 - 90
First Synthesis of Methyl 2-Amino-6-Methoxynicotinate Using a Combination of Microwave and Flow Reaction Technologies
Tymoshenko D. et al, (2011), Synlett, 2011, 203 - 206
Enhanced hit-to-lead process using bioanalogous lead evolution and chemogenomics: application in designing selective matrix metalloprotease inhibitors
Papp Á. et al, (2007), Expert Opinion on Drug Discovery, 2, 707 - 723
Novel chemogenomics approach to design selective enzyme inhibitors
Urge L. et al, (2005), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 229, U148 - U148