Saleta Vazquez Rodriguez
Saleta Vazquez Rodriguez graduated in 2007 in Chemistry at the University of Santiago de Compostela (Spain). She did her final project at the Northern Institute for Cancer Research and at the University of Newcastle Upon Tyne (UK) under the supervision of Prof. Ian Hardcastle, Bernard Golding and Roger Griffin, where she worked in the development of inhibitors for p53-MDM2 interactions.
In 2010 she got an MSc in Organic Chemistry and in 2014 she obtained her PhD in Medicinal Chemistry under the supervision of Prof. Eugenio Uriarte and Prof. Lourdes Santana. Her research field during her PhD was focused on the development of nature inspired oxacycles with pharmacological applications. During her PhD, she developed several stays at the University of Hawai’I at Manoa (USA) under the supervision of Prof. Marcus Tius, and at the University of Porto (Portugal) under the supervision of Fernanda Borges.
In 2014, she developed a postdoctoral research at the University of Porto (Portugal) where she worked on the synthesis of benzopyrone derivatives as antioxdant agents.
In November 2015, Dr. Vazquez Rodriguez joined Paul Brennan’s group as visiting postdoctoral researcher and since 2017, she is a Marie Curie Fellow in his group working on the discovery of new chemical probes for lysine demethylase (KDM) inhibitors as novel epigenetic chemical probes.
Design, Synthesis and Characterization of Covalent KDM5 Inhibitors
Vazquez-Rodriguez S. et al, (2019), Angewandte Chemie International Edition, 58, 515 - 519
Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.
Vazquez-Rodriguez S. et al, (2018), Angew Chem Int Ed Engl
Heterocyclic Antioxidants in Nature: Coumarins
J. Matos M. et al, (2017), Current Organic Chemistry, 21, 311 - 324
Synthesis, antioxidant and antichagasic properties of a selected series of hydroxy-3-arylcoumarins
Robledo-O’Ryan N. et al, (2017), Bioorganic & Medicinal Chemistry, 25, 621 - 632
Facing Chagas' Disease: Trypanocidal Properties of New Coumarinchalcone Scaffolds
Vazquez-Rodriguez S. et al, (2016), Medicinal Chemistry, 12, 537 - 543