Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

portrait

portrait

Megat Abd Hamid

Postdoctoral Research Scientist

DPhil; B.Biotech (Hons)

My research focus is on understanding the characteristics and underlying mechanisms of co-inhibitory and co-stimulatory receptors on cancer-specific cytotoxic T cells and how this could be manipulated for future cancer immunotherapies. Primarily, I am looking into:

1. Distribution of HLA-E and its inhibitory receptors CD94/NKG2a and exploitation of this machinery by cancer to inhibit anti-tumor T cell responses.

2. Importance of self-sustain, highly energetic CD103+ tissue resident memory T cells in anti-tumor responses

3. Epigenetic regulation of effector cytokine responses of cancer-specific T cells.