Seminars

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Sun 23 Sep 2018 from 11:00 to 12:00

Tropical Medicine Seminars

Keble College, Parks Road OX1 3PG

Medicine Quality & Public Health Conference

A pioneering academic conference that aims to bring together, for the first time, people from all over the world dealing with the problem of poor quality medicines and their impact on public health. The conference will provide a unique opportunity for health authorities, scientists, pharmacists,... Read more

A pioneering academic conference that aims to bring together, for the first time, people from all over the world dealing with the problem of poor quality medicines and their impact on public health. The conference will provide a unique opportunity for health authorities, scientists, pharmacists, lawyers and international organisations to discuss the problem and outline the necessary steps to tackle the issue on a global scale.

Booking Required

Audience: Members of the University only

Mon 24 Sep 2018 from 12:00 to 13:00

Kennedy Institute Seminars

Kennedy Institute of Rheumatology, Bernard Sunley Lecture Theatre, Headington OX3 7LF

TNF signalling in T cells - RIPping yarns of new survival pathways

Prof Benedict Seddon

The role that NF-kB signalling plays in the development and function of T cells has been much studied, but remains poorly understood. Our work reveals that the T cell receptor is not the dominant receptor triggering NF-kB signalling during development of T cells, contrary to accepted dogma, but is... Read more

The role that NF-kB signalling plays in the development and function of T cells has been much studied, but remains poorly understood. Our work reveals that the T cell receptor is not the dominant receptor triggering NF-kB signalling during development of T cells, contrary to accepted dogma, but is rather TNF. We also reveal that TNF regulates survival and development of T cells by both NF-kB dependent and independent mechanisms and identify a new survival pathway in T cells, dependent on RIPK1. ---- I had the good fortune to undertake a PhD with Prof Don Mason at the former Medical Research Council's Cellular Immunology Unit, at the Sir William Dunn School of Pathology in Oxford University. We studied the role and mechanisms of regulatory T cells in the control of autoimmunity in rats. I then moved to the MRCs National Institute for Medical Research where I worked first as a post-doc with Dr Rose Zamoyska in the Division of Molecular Immunology, and then started my independent research group as a Programme Leader in the Division of Immune Cell Biology. 10 years at NIMR allowed me to establish a research programme investigating the mechanisms of T cell homeostasis, generating novel genetic models of TCR and cytokine signalling, employing mathematical approaches to gain systems level understanding and identifying novel roles for inflammatory signalling for T cell maturation. In 2013, I relocated the lab to the Institute of Immunity and Transplantation at the Royal Free Hospital Campus of University College London, where I am investigating the role of TNFSFR signalling and NF-kappaB transcription factors in the maturation and function of T cells in health and disease.

Audience: Members of the University only

Organisers: Laura Sánchez Lazo

Tue 25 Sep 2018 from 12:30 to 19:00

Centre for Personalised Medicine Seminars

St Anne's College, Mary Ogilvie Lecture Theatre (MOLT), Woodstock Road OX2 6HS

Personalised Neuroscience: from Molecules to Medicine

Professor Richard Gilbertson, Professor Robert McLaren, Professor Andrea Németh, Dr Sally Cowley, Dr Brent Ryan, Professor Caleb Webber, Professor Jeffrey Golden

The Centre for Personalised Medicine is proud to host a symposium on personalised neuroscience with the very generous support of the Dr Stanley Ho Medical Development Foundation. The symposium will feature three internationally recognised leaders in the field. Professor Robert McLaren will describe... Read more

The Centre for Personalised Medicine is proud to host a symposium on personalised neuroscience with the very generous support of the Dr Stanley Ho Medical Development Foundation. The symposium will feature three internationally recognised leaders in the field. Professor Robert McLaren will describe gene correction in blindness, Professor Richard Gilbert will speak on personalised medicine and brain cancer and Professor Jeffrey Golden will discuss the integration of personalised medicine and neuropathology. The symposium will also feature short talks on induced pluripotential stem cells in brain disease modelling, how individual mutations can lead to neurological symptoms and the use of bioinformatics in patient stratification. http://www.well.ox.ac.uk/cpm/personalised-neuroscience-from-molecules-to-medicine

Booking Required

Audience: All interested people are invited to attend.

Organisers: Catherine Lidbetter

Wed 26 Sep 2018 from 10:00 to 11:00

Tropical Medicine Global Health Seminars

NDM Building, Basement Seminar Room, Headington OX3 7FZ

Human Challenge Studies in Endemic Settings - Malaria and Dengue

Dr Melissa Kapulu, Professor Bridget Wills

Title: Unravelling the course of malaria infections: Controlled Human Malaria Infection in Semi-Immune Adults Speaker: Dr Melissa Kapulu Melissa Kapulu is a post-doc based at the KEMRI-Wellcome Trust Research Programme in Kilifi. Before taking up the post, she read for a DPhil on malaria... Read more

Title: Unravelling the course of malaria infections: Controlled Human Malaria Infection in Semi-Immune Adults Speaker: Dr Melissa Kapulu Melissa Kapulu is a post-doc based at the KEMRI-Wellcome Trust Research Programme in Kilifi. Before taking up the post, she read for a DPhil on malaria transmission-blocking vaccines in Adrian Hill's lab, Jenner Institute, University of Oxford. Prior to this, she had attended the University of Zambia where she undertook a BSc in Molecular Biology and Genetics and an MSc in Immunology of Infectious Diseases at the London School of Hygiene and Tropical Medicine. She is currently involved in establishing, conducting and leading work on controlled human malaria infection studies to study blood-stage growth and transmissibility to msoquitoes. Her main interests are in understanding and characterising signatures of malaria transmission by looking for molecular and immunological markers that can be developed as tools for detecting and preventing human-to-mosquito malaria transmissibility potential. Title: The Challenges of Developing a Dengue Human Infection Model in an Endemic Setting Speaker: Professor Bridget Wills Bridget Wills is Professor of Tropical Medicine at the University of Oxford and Head of the Dengue Research Group at the Oxford University Clinical Research Unit in Ho Chi Minh City, Vietnam. Her work focuses primarily on clinical studies designed to improve diagnosis and management of dengue, together with research to understand the underlying pathophysiological mechanisms of the disease.

Audience: Members of the University only

Organisers: Georgina Humphreys

Fri 28 Sep 2018 from 09:15 to 10:15

MRC HIU Friday Morning Lab Meetings

MRC Weatherall Institute of Molecular Medicine, WIMM Seminar Room, Headington OX3 9DS

The lymphatics: a gateway to immune responses and cancer metastasis

Dr Louise Johnson

Audience: Members of the University only

Organisers: Anne Farmer

Fri 28 Sep 2018 from 13:00 to 14:00

NDM Seminar Series

Henry Wellcome Building of Cellular and Molecular Physiology, Seminar Rooms A & B, Roosevelt Drive OX3 7BN

Tropical Medicine Seminar: First Seminar: Malaria Models and Policy: Letters from Thailand. 2nd Seminar: Data sharing: easier said than done!

Prof Lisa White, Professor Phaik Yeong Cheah

Audience: Members of the University only

Organisers: Kathryn Smith

Fri 28 Sep 2018 from 13:00 to 14:00

WIMM Science Career Seminars

MRC Weatherall Institute of Molecular Medicine, Seminar room, Headington OX3 9DS

Embracing Fear and Rejection – How I become an Editor

Dr Carolina Perdigoto

Audience: Members of the University only

Organisers: WIMM Postdoc Association