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The influenza virus was instrumental in unravelling critical aspects of the antiviral T lymphocyte mediated immune response. A major finding was the demonstration that CD8 T lymphocytes recognize short viral peptides presented by class I molecules of the major histocompatibility complex. Studies of influenza specific T cells have also led to an understanding of their important role in recovery from influenza virus infection in humans.

Original publication

DOI

10.1016/j.bj.2018.08.003

Type

Journal article

Journal

Biomed J

Publication Date

08/2018

Volume

41

Pages

242 - 248

Keywords

Influenza, T lymphocytes