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Pragmin is a catalytically inactive pseudo-kinase that is important in regulating cellular growth and adhesion. In this issue of Structure, Lecointre et al. (2018) present the structure of Pragmin, illustrating a dimerization domain flanking its pseudo-kinase domain that is important for Pragmin-mediated activation of the non-receptor tyrosine kinase CSK.

Original publication

DOI

10.1016/j.str.2018.03.008

Type

Journal article

Journal

Structure

Publication Date

03/04/2018

Volume

26

Pages

527 - 528