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Quantification studies of complex protein mixtures have been restricted mainly to whole cell extracts. Here we describe the synthesis of two sets of isotope-coded activity-based probes that allow quantitative functional proteomics experiments on the cathepsins.

Original publication

DOI

10.1016/j.bmcl.2004.04.046

Type

Journal article

Journal

Bioorg Med Chem Lett

Publication Date

21/06/2004

Volume

14

Pages

3131 - 3134

Keywords

Cysteine Endopeptidases, Isotope Labeling, Isotopes, Proteomics