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Combination antiretroviral therapy during primary human immunodeficiency virus-1 infection may enable long-term drug-free virological control in rare individuals. We describe a female who maintained aviremia and a normal CD4(+)/CD8(+) T cell ratio for 10 years after stopping therapy, despite a persistent viral reservoir. Cellular immune responses may have contributed to this outcome.

Original publication

DOI

10.1093/ofid/ofv144

Type

Journal article

Journal

Open Forum Infect Dis

Publication Date

12/2015

Volume

2

Keywords

CD8 T cell, HIV-1 reservoir, antiretroviral therapy, primary HIV-1 infection, viral inhibition assay