Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
Skip to main content

Benzoselenadiazole-containing inhibitors of protein kinases were constructed and their capability to emit phosphorescence in the kinase-bound state was established. Labelling of the inhibitors with a red fluorescent dye led to sensitive responsive photoluminescent probes for protein kinase CK2 that emitted red light with a long (microsecond-scale) decay time upon excitation of the probes with a pulse of near-UV light.

Original publication

DOI

10.1039/c3cc49198f

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

21/04/2014

Volume

50

Pages

4096 - 4098

Keywords

Azoles, Casein Kinase II, Coloring Agents, Cyclic AMP-Dependent Protein Kinases, Light, Organoselenium Compounds, Peptides, Proto-Oncogene Proteins c-pim-1