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Twenty years after the discovery of HIV, there is still no vaccine. This year, an envelope vaccine aimed at stimulating neutralizing antibodies was unable to protect against infection in phase 3 trials. But more than 20 HIV vaccines designed to stimulate T-cell responses are being developed. Will any of them work?

Original publication

DOI

10.1038/nm0703-874

Type

Journal article

Journal

Nat Med

Publication Date

07/2003

Volume

9

Pages

874 - 880

Keywords

AIDS Vaccines, Antibodies, CD8-Positive T-Lymphocytes, Clinical Trials as Topic, Drug Design, HIV, Humans, T-Lymphocytes, Vaccines, Synthetic