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We report the possible transmission of drug-resistant human immunodeficiency virus type 2. A 66-year-old woman from rural Guinea Bissau who had no obvious antiretroviral exposure was found to harbor a variant with the multidrug-resistance mutation Q151M. Finding this mutation among a drug-naive population presents an important public health issue that needs to be addressed for treatment to be effective.

Original publication

DOI

10.1086/599107

Type

Journal article

Journal

Clin Infect Dis

Publication Date

15/06/2009

Volume

48

Pages

1790 - 1793

Keywords

Aged, Amino Acid Substitution, Anti-HIV Agents, Drug Resistance, Multiple, Viral, Female, Guinea-Bissau, HIV Infections, HIV-2, Humans, Molecular Sequence Data, Mutation, Missense, Sequence Analysis, DNA