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SETTING: Although tuberculosis (TB) is a curable disease, it remains a major global health problem and an important cause of morbidity and mortality among vulnerable populations, including refugees and migrants. OBJECTIVE: To describe results and experiences over 20 years at a TB programme in refugee camps on the Thai-Burmese border in Tak Province, Thailand, and to identify risk factors associated with adverse outcomes (e.g., default, failure, death). DESIGN: Retrospective review of routine records of 2425 patients admitted for TB treatment in the Mae La TB programme between May 1987 and December 2005. RESULTS: TB cases notified among refugees decreased over 20 years. Among patients treated with a first-, second- or third-line regimen, 77.5% had a successful outcome, 13.5% defaulted, 7.6% died and 1.3% failed treatment. Multivariate analysis for new cases showed higher likelihood of adverse outcomes for patients who were Burmese migrants or Thai villagers, male, aged >15 years or with smear-negative pulmonary TB. CONCLUSION: These findings suggest that treatment outcomes depend on the programme's capacity to respond to specific patients' constraints. High-risk groups, such as migrant populations, need a patient-centred approach, and specific, innovative strategies have to be developed based on the needs of the most vulnerable and marginalised populations.

Type

Journal article

Journal

Int J Tuberc Lung Dis

Publication Date

12/2010

Volume

14

Pages

1589 - 1595

Keywords

Adolescent, Adult, Antitubercular Agents, Child, Female, Humans, Male, Middle Aged, Multivariate Analysis, Myanmar, Patient-Centered Care, Refugees, Retrospective Studies, Risk Factors, Sputum, Thailand, Transients and Migrants, Treatment Failure, Treatment Outcome, Tuberculosis, Tuberculosis, Pulmonary, Young Adult