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Publications

Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L

Zhu K. et al, (2024), EMBO Reports

Multi-omics analysis of virus-permissive versus hostile cellular states reveals protein networks controlling virus infection

Chen H. et al, (2024)

Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response.

Lee AA. et al, (2024)

Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair

Yang H. et al, (2024), Science Advances, 10

Hif-2α programmes oxygen chemosensitivity in chromaffin cells

Prange-Barczynska M. et al, (2024), Journal of Clinical Investigation

Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus

Sauer D. et al, (2024)

Characterisation of HBV and co-infection with HDV and HIV through spatial transcriptomics.

Cross A. et al, (2024), eGastroenterology, 2

Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity.

Singh S. et al, (2024)

Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors.

Mackinnon SR. et al, (2024), Biochimie

Editorial: Beyond protein degradation and lysine modification: novel insights into non-canonical ubiquitination

Sapmaz A. et al, (2024), Frontiers in Molecular Biosciences, 11

Paralogue-Selective Degradation of the Lysine Acetyltransferase EP300

Chen X. et al, (2024), JACS Au

Adaptor protein 2 sigma subunit (AP2S1) variants associated with neurodevelopmental disorders

Stevenson M. et al, (2024)

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor

O’Brien DP. et al, (2024)

A ligand discovery toolbox for the WWE domain family of human E3 ligases.

Münzker L. et al, (2024), Communications biology, 7

Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors.

Kent D. et al, (2024), Hepatology (Baltimore, Md.)

Deubiquitinases in muscle physiology and disorders

Olie CS. et al, (2024), Biochemical Society Transactions, 52, 1085 - 1098

Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank.

Lassen FH. et al, (2024), Cell Genom

N-terminal cysteine acetylation and oxidation patterns may define protein stability

Heathcote KC. et al, (2024), Nature Communications, 15

Lysosomal signalling pathways influence heart rhythm, and regulate atrial function

Burton REBECCA. et al, (2024)

Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients

Stieger A. et al, (2024), Metabolites, 14, 334 - 334

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