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<ns4:p>The human immunodeficiency virus (HIV) evolves rapidly owing to the combined activity of error-prone reverse transcriptase, recombination, and short generation times, leading to extensive viral diversity both within and between hosts. This diversity is a major contributing factor in the failure of the immune system to eradicate the virus and has important implications for the development of suitable drugs and vaccines to combat infection. This review will discuss the recent technological advances that have shed light on HIV evolution and will summarise emerging concepts in this field.</ns4:p>

Original publication

DOI

10.12688/f1000research.10876.1

Type

Journal article

Journal

F1000Research

Publisher

F1000 ( Faculty of 1000 Ltd)

Publication Date

28/04/2017

Volume

6

Pages

597 - 597