Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

<jats:p>How cells integrate antagonistic receptor signaling events is enigmatic. Using superresolution optical microscopy, Lopes et al. (2017. <jats:italic>J. Cell Biol.</jats:italic><jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="https://doi.org/10.1083/jcb.201608094" ext-link-type="uri">https://doi.org/10.1083/jcb.201608094</jats:ext-link>) demonstrate the nanometer-scale molecular reorganization of antagonistic signaling receptors in macrophages, after engagement by the receptors of activating and inhibitory ligands. They propose that large-scale rearrangements of this type underpin decision-making by these cells.</jats:p>

Original publication

DOI

10.1083/jcb.201702028

Type

Journal article

Journal

The Journal of Cell Biology

Publisher

Rockefeller University Press

Publication Date

03/04/2017

Volume

216

Pages

871 - 873