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The susceptibility of common marmosets and cotton-top tamarins to infection by HIV-2 in vivo was tested. One year and 19 months, respectively, post-inoculation, sera taken from three of four animals from each species are reactive for HIV-2 antibodies and HIV-specific nucleotide sequences were demonstrated in short-term cultures of PBL from two cotton-top tamarins. The animals remain in good health.

Type

Journal article

Journal

J Med Primatol

Publication Date

1989

Volume

18

Pages

329 - 335

Keywords

Acquired Immunodeficiency Syndrome, Animals, Aotus trivirgatus, Blotting, Southern, Blotting, Western, Callithrix, Callitrichinae, Cebidae, DNA, Viral, Disease Models, Animal, Enzyme-Linked Immunosorbent Assay, HIV Antibodies, HIV-1, HIV-2, Nucleic Acid Hybridization, Saguinus