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<jats:p>Two hybrids between the alkaloids bauerine C and rutaecarpine were prepared. Screening for cytotoxic activity revealed that introduction of two chlorine substituents to the quinazolinocarboline core of rutaecarpine strongly enhances cytotoxic activity, whereas methylation at the indole nitrogen is detrimental to activity.</jats:p>

Original publication

DOI

10.1515/znb-2007-1013

Type

Journal article

Journal

Zeitschrift für Naturforschung B

Publisher

Walter de Gruyter GmbH

Publication Date

01/10/2007

Volume

62

Pages

1313 - 1316