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Interview with Chas Bountra and Peter Ratcliffe. 'The world urgently needs new medicines for many diseases', says Professor Chas Bountra, 'the fundamental bottleneck is our ability to identify new targets for drug discovery.' Professor Peter Ratcliffe is of exactly the same mind: 'In starting drug development you need to start in the right place. We need to have the right molecular target.' The new Target Discovery Institute aims to validate targets for drug discovery.